Behavioral Effects of Endocrine-disrupting Substances: Phytoestrogens

Endocrine disrupting effects in rats perinatally exposed to a dietary relevant mixture of phytoestrogens.

Dietary phytoestrogens may prevent certain human diseases, but endocrine activity has been reported in animal studies. Sprague-Dawley rats were exposed perinatally to a 1-, 10- or 100-fold "high human dietary intake" mixture of 12 phytoestrogens consisting of mainly the lignan secoisolarici resinol and the isoflavones genistein and daidzein. This mixture induced persistent adverse effects, as a...

Endocrine disrupting chemicals: harmful substances and how to test them.

This paper presents an analysis of the opinions of different groups from: scientists, international regulatory bodies, non-governmental organizations and industry; with an interest in the problem of identifying chemical substances with endocrine disrupting activity. There is also discussion of the consequences that exposure to endocrine disruptors may have for human health, considering concrete...

Effects of Endocrine Disrupting Chemicals on Seals

At the same time harbour porpoises, that had died of a similar virus, appeared stranded on the beaches. Two years later another mass die-off occurred in the Mediterranean striped dolphin populations. The severe and lethal outcomes of the epidemics led many in the scientific community to believe that a contaminantinduced immune deficiency was responsible for the high mortality during the epidemi...

Endocrine disrupting chemicals

The idea that xenobiotic chemicals could inappropriately modlate the endocrine system thereby causing detrimental effects n wildlife and humans was first proposed 20 years ago at the atershed Wingspread Conference [1,2]. These endocrine disruptng chemicals (EDCs) have long been controversial, with a great eal of discussion raging in the scientific literature. Much of this ontroversy has centere...

Endocrine Disrupting Pesticides